Gene

mark2b

ID
ZDB-GENE-080215-4
Name
MAP/microtubule affinity-regulating kinase 2b
Symbol
mark2b Nomenclature History
Previous Names
  • mark2
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in intracellular signal transduction and microtubule cytoskeleton organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in dendrite. Predicted to be active in cytoplasm. Orthologous to human MARK2 (microtubule affinity regulating kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la025900TgTransgenic insertionUnknownUnknownDNA
sa9740Allele with one point mutationUnknownPremature StopENU
sa34062Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With mark2b Human Ortholog
No data available
Associated With mark2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001772 Kinase associated domain 1 (KA1)
Domain IPR015940 Ubiquitin-associated domain
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Domain Details Per Protein
Protein Length KA1 domain/Ssp2, C-terminal Kinase associated domain 1 (KA1) Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase MARK 1-4, catalytic domain Ubiquitin-associated domain
UniProtKB:A0A8M3B425 781
UniProtKB:A0A8M3BAZ3 768
UniProtKB:A0A8M3AU60 741
UniProtKB:A0A8M3AU67 777
UniProtKB:A0A8M3AU54 789
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 7
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mark2-201 (1) Ensembl 539 nt
mRNA mark2b-201 (1) Ensembl 2,343 nt
mRNA mark2b-202 (1) Ensembl 2,304 nt
mRNA mark2b-203 (1) Ensembl 655 nt
mRNA mark2b-205 (1) Ensembl 5,075 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-226L4ZFIN Curated Data
Contained inBACDKEY-269E10ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMARK211
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseMark219
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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