Gene
zgc:174259
- ID
- ZDB-GENE-080213-10
- Name
- zgc:174259
- Symbol
- zgc:174259 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1) and SERPINA12 (serpin family A member 12).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR023795 | Serpin, conserved site |
Domain | IPR023796 | Serpin domain |
Family | IPR000215 | Serpin family |
Homologous_superfamily | IPR036186 | Serpin superfamily |
Homologous_superfamily | IPR042178 | Serpin superfamily, domain 1 |
Homologous_superfamily | IPR042185 | Serpin superfamily, domain 2 |
Domain Details Per Protein
Protein | Length | Serpin, conserved site | Serpin domain | Serpin family | Serpin superfamily | Serpin superfamily, domain 1 | Serpin superfamily, domain 2 |
---|---|---|---|---|---|---|---|
UniProtKB:F8W298
|
|||||||
UniProtKB:A9JSZ7
|
|||||||
UniProtKB:A0A8M9PKK0
|
410 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
zgc:174259-201
(1)
|
Ensembl | 1,419 nt | ||
mRNA |
zgc:174259-202
(1)
|
Ensembl | 1,505 nt |
Interactions and Pathways
No data available
Plasmids
No data available