Gene

foxred1

ID

ZDB-GENE-080204-64

Name

FAD-dependent oxidoreductase domain containing 1

Symbol

foxred1 Nomenclature History

Previous Names

zgc:172243

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 19. Orthologous to human FOXRED1 (FAD dependent oxidoreductase domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With foxred1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 19	Alliance	Mitochondrial complex I deficiency, nuclear type 19	618241

1 - 1 of 1

Associated With foxred1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006076	FAD dependent oxidoreductase
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily

1 - 2 of 2

Domain Details Per Protein

Protein	Additional Resources	Length	FAD dependent oxidoreductase	FAD/NAD(P)-binding domain superfamily
UniProtKB:A8WG78	InterPro	492

1 - 1 of 1

Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 10

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	foxred1-201 (1) Ensembl	Ensembl	2,490 nt	Select Tool ZFIN BLAST
mRNA	foxred1-202 (1) Ensembl	Ensembl	1,787 nt	Select Tool ZFIN BLAST
mRNA	foxred1-203 (1) Ensembl	Ensembl	1,495 nt	Select Tool ZFIN BLAST

1 - 3 of 3

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH73-232H9	CU633782	ZFIN Curated Data
Encodes	cDNA	MGC:172243	BC154609	ZFIN Curated Data
Encodes	cDNA	MGC:198154	BC171427	ZFIN Curated Data
Encodes	cDNA	MGC:198156	BC171429	ZFIN Curated Data

1 - 4 of 4

Show

Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001113578 (1)	2519 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU633782 (1)	104199 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A8WG78 (1)	492 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	FOXRED1	11	Ensembl:ENSG00000110074 Gene:55572 HGNC:26927 OMIM:613622	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Foxred1	9	Ensembl:ENSMUSG00000039048 Gene:235169 MGI:2446262	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

1 - 1 of 1

Show