Gene
aspa
- ID
- ZDB-GENE-080204-11
- Name
- aspartoacylase
- Symbol
- aspa Nomenclature History
- Previous Names
-
- zgc:171507
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Canavan disease. Orthologous to human ASPA (aspartoacylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Canavan disease | Alliance | Canavan disease | 271900 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AspA/AstE family amino acid metabolism and detoxification | Aspartoacylase | Succinylglutamate desuccinylase/aspartoacylase |
|---|---|---|---|---|
|
UniProtKB:A8KB34
|
315 |
Interactions and Pathways
No data available
Plasmids
No data available