Gene

naxd

ID

ZDB-GENE-080204-1

Name

NAD(P)HX dehydratase

Symbol

naxd Nomenclature History

Previous Names

carkd (1)
zgc:171429

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have ADP-dependent NAD(P)H-hydrate dehydratase activity; ATP binding activity; and ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in nicotinamide nucleotide metabolic process. Orthologous to human NAXD (NAD(P)HX dehydratase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With naxd Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 2	618321

Associated With naxd Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017953	Carbohydrate kinase, predicted, conserved site
Domain	IPR000631	ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase
Domain	IPR044822	Myb/SANT-like DNA-binding domain 4
Homologous_superfamily	IPR029056	Ribokinase-like

Domain Details Per Protein

Protein	Length	ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase	Carbohydrate kinase, predicted, conserved site	Myb/SANT-like DNA-binding domain 4	Ribokinase-like
UniProtKB:F1Q575 InterPro	330
UniProtKB:E7F490 InterPro	625
UniProtKB:A0A8M2BEU7 InterPro	336
UniProtKB:A0A8M2BEY3 InterPro	470
UniProtKB:A0A8M2BEU4 InterPro	621
UniProtKB:A0A8M2BET0 InterPro	482
UniProtKB:A0A8M2BFH6 InterPro	480
UniProtKB:A8KB11 InterPro	424
UniProtKB:A0A8M2BEW7 InterPro	615

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	naxd-201 (1) Ensembl	Ensembl	1,573 nt	Select Tool ZFIN BLAST
mRNA	naxd-202 (1) Ensembl	Ensembl	3,053 nt	Select Tool ZFIN BLAST
mRNA	naxd-203 (1) Ensembl	Ensembl	698 nt	Select Tool
mRNA	naxd-204 (1) Ensembl	Ensembl	796 nt	Select Tool
mRNA	naxd-205 (1) Ensembl	Ensembl	1,060 nt	Select Tool
mRNA	naxd-206 (1) Ensembl	Ensembl	677 nt	Select Tool
mRNA	naxd-207 (1) Ensembl	Ensembl	910 nt	Select Tool
mRNA	naxd-208 (1) Ensembl	Ensembl	876 nt	Select Tool
mRNA	naxd-209 (1) Ensembl	Ensembl	1,753 nt	Select Tool
mRNA	naxd-210 (1) Ensembl	Ensembl	1,030 nt	Select Tool
mRNA	naxd-211 (1) Ensembl	Ensembl	1,431 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations