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General Information
ZIRC
ZFIN ID: ZDB-GENE-080108-5
Gene Name: dedicator of cytokinesis 1
Gene Symbol: dock1
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Involved in myelination in peripheral nervous system and myoblast fusion. Predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22170 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28011 Point Mutation Unknown Premature Stop ENU
    sa31895 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • stl145 Point Mutation Unknown Unknown ENU
    stl365 Insertion Unknown Unknown TALEN
    stl366 Small Deletion Unknown Unknown TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH dock1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dock1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myelination in peripheral nervous system (more)
    Cellular Component integral component of membrane (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 9)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dock1-001 (1) 1143
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dock1 No data available
    MARKER RELATIONSHIPS
    dock1Contained in: [BAC] CH211-232H12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110011 (1) 5904bp
    Genomic GenBank:CR848039 (1) 154190bp
    Select Tool
    Polypeptide UniProtKB:A8E1V6 (1) 1866aa
    Sequence Clusters UniGene:151687 (1)
    Sequence Information (all 43)
    ORTHOLOGY for dock1 (Chr: 12)
    CITATIONS (18)