Gene
il6r
- ID
- ZDB-GENE-080107-7
- Name
- interleukin 6 receptor
- Symbol
- il6r Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in several structures, including epidermis; immune system; lateral line; liver; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 8 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR003530 | Long hematopoietin receptor, soluble alpha chain, conserved site |
Domain | IPR003961 | Fibronectin type III |
Family | IPR050379 | Type I Cytokine Receptor |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Long hematopoietin receptor, soluble alpha chain, conserved site | Type I Cytokine Receptor |
---|---|---|---|---|---|---|---|
UniProtKB:A0A7S9AT90
|
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UniProtKB:A0A7S9ATA7
|
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UniProtKB:A0A8M1PAC4
|
604 |
- Genome Browsers
Interactions and Pathways
Plasmids
No data available