Gene

il12rb2

ID

ZDB-GENE-080107-3

Name

interleukin 12 receptor, beta 2a

Symbol

il12rb2 Nomenclature History

Previous Names

il12rb2a (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and positive regulation of cell population proliferation. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL12RB2 (interleukin 12 receptor subunit beta 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Liongue et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With il12rb2 Human Ortholog

No data available

Associated With il12rb2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003961	Fibronectin type III
Domain	IPR015321	Type I cytokine receptor, cytokine-binding domain
Family	IPR052672	Type I Cytokine Receptor Family, Type 2 Subfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily