ZFIN is now using GRCz12tu for Genomic Data
Gene
nlgn3a
- ID
- ZDB-GENE-071219-1
- Name
- neuroligin 3a
- Symbol
- nlgn3a Nomenclature History
- Previous Names
-
- nlgn3b (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be active in cell surface; plasma membrane; and synapse. Is expressed in several structures, including brain; cranial ganglion; eye; gonad; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN3 (neuroligin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism susceptibility, X-linked 1} | 300425 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QB35 | InterPro | 858 | |||||
| UniProtKB:A0A0R4IJ74 | InterPro | 878 | |||||
| UniProtKB:A0A0R4IQV1 | InterPro | 838 | |||||
| UniProtKB:D0EVX1 | InterPro | 815 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nlgn3a-201
(1)
|
Ensembl | 2,754 nt | ||
| mRNA |
nlgn3a-202
(1)
|
Ensembl | 4,525 nt | ||
| mRNA |
nlgn3a-203
(1)
|
Ensembl | 3,367 nt | ||
| mRNA |
nlgn3a-204
(1)
|
Ensembl | 3,307 nt | ||
| mRNA |
nlgn3a-205
(1)
|
Ensembl | 2,448 nt | ||
| mRNA |
nlgn3a-206
(1)
|
Ensembl | 3,307 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers