Gene
itgb3a
- ID
- ZDB-GENE-071207-1
- Name
- integrin beta 3a
- Symbol
- itgb3a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to localize to cell surface; focal adhesion; and integrin complex. Human ortholog(s) of this gene implicated in several diseases, including autoimmune thrombocytopenic purpura; blood platelet disease (multiple); end stage renal failure; non-arteritic anterior ischemic optic neuropathy; and platelet-type bleeding disorder 16. Is expressed in brain and pectoral fin. Orthologous to human ITGB3 (integrin subunit beta 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR002369 | Integrin beta subunit, VWA domain |
Domain | IPR012896 | Integrin beta subunit, tail |
Domain | IPR014836 | Integrin beta subunit, cytoplasmic domain |
Domain | IPR016201 | PSI domain |
Domain | IPR033760 | Integrin beta N-terminal |
Domain | IPR040622 | Integrin beta, epidermal growth factor-like domain 1 |
Family | IPR015812 | Integrin beta subunit |
Homologous_superfamily | IPR032695 | Integrin domain superfamily |
Homologous_superfamily | IPR036349 | Integrin beta tail domain superfamily |
Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
Protein | Length | Integrin beta, epidermal growth factor-like domain 1 | Integrin beta N-terminal | Integrin beta subunit | Integrin beta subunit, cytoplasmic domain | Integrin beta subunit, tail | Integrin beta subunit, VWA domain | Integrin beta tail domain superfamily | Integrin domain superfamily | PSI domain | von Willebrand factor A-like domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q3LTM4
|
785 |
- Genome Browsers
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
itgb3a-201
(1)
|
Ensembl | 2,535 nt |
Interactions and Pathways
No data available
Plasmids
No data available