Gene

traf5

ID

ZDB-GENE-071120-3

Name

Tnf receptor-associated factor 5

Symbol

traf5 Nomenclature History

Previous Names

si:ch211-284e20.7

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have enzyme binding activity; tumor necrosis factor receptor binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to cytoplasmic side of plasma membrane. Orthologous to human TRAF5 (TNF receptor associated factor 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With traf5 Human Ortholog

No data available

Associated With traf5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR001293	Zinc finger, TRAF-type
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR002083	MATH/TRAF domain
Domain	IPR018957	Zinc finger, C3HC4 RING-type
Domain	IPR049342	TRAF1-6, MATH domain
Family	IPR012227	TNF receptor-associated factor TRAF, metazoa
Homologous_superfamily	IPR008974	TRAF-like
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Length	MATH/TRAF domain	TNF receptor-associated factor TRAF, metazoa	TRAF1-6, MATH domain	TRAF-like	Zinc finger, C3HC4 RING-type	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site	Zinc finger, TRAF-type
UniProtKB:A0A8M9PEP5 InterPro	542

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	traf5-201 (1) Ensembl	Ensembl		1,336 nt	Select Tool ZFIN BLAST
mRNA	traf5-202 (1) Ensembl	Ensembl		1,011 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations