Gene
epor
- ID
- ZDB-GENE-071116-1
- Name
- erythropoietin receptor
- Symbol
- epor Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have transmembrane signaling receptor activity. Involved in hemopoiesis and pronephros development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in anemia; familial erythrocytosis 1; malignant glioma; polycythemia; and systemic lupus erythematosus. Is expressed in several structures, including digestive system; hematopoietic cell; hematopoietic system; kidney; and lateral plate mesoderm. Orthologous to human EPOR (erythropoietin receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial erythrocytosis 1 | Alliance | [Erythrocytosis, familial, 1] | 133100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Erythropoietin receptor | Fibronectin type III | Fibronectin type III superfamily | Growth hormone/erythropoietin receptor, ligand binding | Immunoglobulin-like fold |
|---|---|---|---|---|---|---|
|
UniProtKB:Q2VBQ8
|
509 |
Interactions and Pathways
No data available
Plasmids
No data available