Gene
dntt
- ID
- ZDB-GENE-071020-1
- Name
- deoxynucleotidyltransferase, terminal
- Symbol
- dntt Nomenclature History
- Previous Names
-
- TdT (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have DNA-directed DNA polymerase activity. Predicted to be involved in base-excision repair and double-strand break repair via nonhomologous end joining. Predicted to localize to nucleus. Is expressed in intestine; kidney; spleen; and thymus.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Beetz et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR019843 | DNA polymerase family X, binding site |
| Domain | IPR001357 | BRCT domain |
| Domain | IPR002054 | DNA-directed DNA polymerase X |
| Domain | IPR010996 | DNA polymerase beta-like, N-terminal domain |
| Domain | IPR018944 | DNA polymerase lambda, fingers domain |
| Domain | IPR028207 | DNA polymerase beta, palm domain |
| Domain | IPR029398 | DNA polymerase beta, thumb domain |
| Family | IPR001726 | DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu |
| Family | IPR022312 | DNA polymerase family X |
| Family | IPR027292 | DNA nucleotidylexotransferase (TdT) |
| Homologous_superfamily | IPR027421 | DNA polymerase lambda lyase domain superfamily |
| Homologous_superfamily | IPR036420 | BRCT domain superfamily |
| Homologous_superfamily | IPR037160 | DNA polymerase, thumb domain superfamily |
| Homologous_superfamily | IPR043519 | Nucleotidyltransferase superfamily |
Domain Details Per Protein
| Protein | Length | BRCT domain | BRCT domain superfamily | DNA-directed DNA polymerase X | DNA nucleotidylexotransferase (TdT) | DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu | DNA polymerase beta-like, N-terminal domain | DNA polymerase beta, palm domain | DNA polymerase beta, thumb domain | DNA polymerase family X | DNA polymerase family X, binding site | DNA polymerase lambda, fingers domain | DNA polymerase lambda lyase domain superfamily | DNA polymerase, thumb domain superfamily | Nucleotidyltransferase superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5J2Q9
|
487 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available