Gene
ttc12
- ID
- ZDB-GENE-071016-4
- Name
- tetratricopeptide repeat domain 12
- Symbol
- ttc12 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human TTC12 (tetratricopeptide repeat domain 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 45 | Alliance | Ciliary dyskinesia, primary, 45 | 618801 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR043195 | Tetratricopeptide repeat protein 12 |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Repeat | IPR019734 | Tetratricopeptide repeat |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Tetratricopeptide repeat protein 12 |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B119
|
707 | |||||
|
UniProtKB:X1WF42
|
700 | |||||
|
UniProtKB:A0A8M3AIH8
|
443 |
Interactions and Pathways
No data available
Plasmids
No data available