Gene

sqlea

ID

ZDB-GENE-071004-98

Name

squalene epoxidase a

Symbol

sqlea Nomenclature History

Previous Names

zgc:171801

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable squalene monooxygenase activity. Predicted to be involved in cholesterol metabolic process and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SQLE (squalene epoxidase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sqlea Human Ortholog

No data available

Associated With sqlea Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013698	Squalene epoxidase
Family	IPR040125	Squalene monooxygenase
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily

Domain Details Per Protein

Protein	Length	FAD/NAD(P)-binding domain superfamily	Squalene epoxidase	Squalene monooxygenase
UniProtKB:A8E4T1 InterPro	557

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	sqlea-201 (1) Ensembl	Ensembl		2,093 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations