Gene
mapre2
- ID
- ZDB-GENE-071004-41
- Name
- microtubule-associated protein, RP/EB family, member 2
- Symbol
- mapre2 Nomenclature History
- Previous Names
-
- zgc:171788 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable microtubule plus-end binding activity. Acts upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be located in cytoplasm and microtubule. Predicted to be active in microtubule cytoskeleton. Human ortholog(s) of this gene implicated in congenital symmetric circumferential skin creases 2. Orthologous to human MAPRE2 (microtubule associated protein RP/EB family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Isrie et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital symmetric circumferential skin creases 2 | Alliance | Symmetric circumferential skin creases, congenital, 2 | 616734 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calponin homology domain | CH domain superfamily | EB1, C-terminal | EB1, C-terminal domain superfamily | Microtubule-associated protein RP/EB |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AW64
|
335 | |||||
|
UniProtKB:A0A8M2BA49
|
291 | |||||
|
UniProtKB:A7MC00
|
343 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mapre2-201
(1)
|
Ensembl | 639 nt | ||
| mRNA |
mapre2-202
(1)
|
Ensembl | 1,032 nt | ||
| mRNA |
mapre2-203
(1)
|
Ensembl | 1,366 nt |
Interactions and Pathways
No data available
Plasmids
No data available