Gene
zgc:171740
- ID
- ZDB-GENE-071004-29
- Name
- zgc:171740
- Symbol
- zgc:171740 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of apoptotic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR055111 | E3 ubiquitin-protein ligase rififylin, HeH domain |
| Family | IPR051728 | RING-FYVE domain-containing E3 ubiquitin-protein ligase |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036361 | SAP domain superfamily |
Domain Details Per Protein
| Protein | Length | E3 ubiquitin-protein ligase rififylin, HeH domain | RING-FYVE domain-containing E3 ubiquitin-protein ligase | SAP domain superfamily | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|
|
UniProtKB:A7MBX4
|
273 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:171740-201
(1)
|
Ensembl | 1,421 nt | ||
| mRNA |
zgc:171740-202
(1)
|
Ensembl | 816 nt |
Interactions and Pathways
No data available
Plasmids
No data available