Gene

dync2i2

ID
ZDB-GENE-070928-9
Name
dynein 2 intermediate chain 2
Symbol
dync2i2 Nomenclature History
Previous Names
  • dync2i1
  • wdr34
  • zgc:171284 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have dynein heavy chain binding activity and dynein light chain binding activity. Involved in intraciliary transport. Predicted to localize to ciliary plasm and cytoplasmic dynein complex. Is expressed in central nervous system; pronephric duct; and retina. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 11 with or without polydactyly. Orthologous to human DYNC2I2 (dynein 2 intermediate chain 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Krock et al., 2009
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Krock et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dync2i2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
short-rib thoracic dysplasia 11 with or without polydactyly Alliance Short-rib thoracic dysplasia 11 with or without polydactyly 615633
Associated With dync2i2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length WD40 repeat WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A3KNL8 481
UniProtKB:A7MD87 501
UniProtKB:E9QDC0 139
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations