Gene
scn2b
- ID
- ZDB-GENE-070920-1
- Name
- sodium channel, voltage-gated, type II, beta
- Symbol
- scn2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have sodium channel regulator activity. Predicted to be involved in ion transport. Predicted to localize to voltage-gated sodium channel complex. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Is expressed in brain; eye; gill; heart; and liver. Orthologous to human SCN2B (sodium voltage-gated channel beta subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chopra et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial atrial fibrillation | Alliance | Atrial fibrillation, familial, 14 | 615378 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR000920 | Myelin P0 protein-related |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain | Myelin P0 protein-related |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q06W28
|
230 |
Interactions and Pathways
No data available
Plasmids
No data available