Gene
tas1r2.1
- ID
- ZDB-GENE-070917-1
- Name
- taste receptor, type 1, member 2, tandem duplicate 1
- Symbol
- tas1r2.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in gill raker; mouth; and pharynx. Orthologous to human TAS1R2 (taste 1 receptor member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ishimaru et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017979 | GPCR, family 3, conserved site |
| Domain | IPR001828 | Receptor, ligand binding region |
| Domain | IPR011500 | GPCR, family 3, nine cysteines domain |
| Domain | IPR017978 | GPCR family 3, C-terminal |
| Family | IPR000068 | GPCR, family 3, extracellular calcium-sensing receptor-related |
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Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, family 3 | GPCR, family 3, conserved site | GPCR family 3, C-terminal | GPCR, family 3, extracellular calcium-sensing receptor-related | GPCR, family 3, nine cysteines domain | GPCR, family 3, nine cysteines domain superfamily | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B0R142 | InterPro | 825 | ||||||||
| UniProtKB:Q2MHL1 | InterPro | 825 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tas1r2.2-201
(1)
|
Ensembl | 2,478 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-196G2 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001039831 (1) | 2478 nt | ||
| Genomic | GenBank:AL935148 (1) | 195396 nt | ||
| Polypeptide | UniProtKB:B0R142 (1) | 825 aa |
- Del Vecchio, G., Murashita, K., Verri, T., Gomes, A.S., Rønnestad, I. (2021) Leptin receptor-deficient (knockout) zebrafish: effects on nutrient acquisition. General and comparative endocrinology. 310:113832
- Ohmoto, M., Okada, S., Nakamura, S., Abe, K., and Matsumoto, I. (2011) Mutually exclusive expression of Gαia and Gα14 reveals diversification of taste receptor cells in zebrafish. The Journal of comparative neurology. 519(8):1616-1629
- Oike, H., Nagai, T., Furuyama, A., Okada, S., Aihara, Y., Ishimaru, Y., Marui, T., Matsumoto, I., Misaka, T., and Abe, K. (2007) Characterization of ligands for fish taste receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(21):5584-5592
- Alioto, T.S., and Ngai, J. (2006) The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids. BMC Genomics. 7(1):309
- Ishimaru, Y., Okada, S., Naito, H., Nagai, T., Yasuoka, A., Matsumoto, I., and Abe, K. (2005) Two families of candidate taste receptors in fishes. Mechanisms of Development. 122(12):1310-1321
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