Gene
kcnab1b
- ID
- ZDB-GENE-070912-690
- Name
- potassium voltage-gated channel subfamily A regulatory beta subunit 1b
- Symbol
- kcnab1b Nomenclature History
- Previous Names
-
- si:dkeyp-94h10.1
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable aldo-keto reductase (NADPH) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in regulation of potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport and potassium ion transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Is expressed in female organism. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023210 | NADP-dependent oxidoreductase domain |
| Family | IPR005399 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
| Family | IPR005400 | Potassium channel, voltage-dependent, beta subunit, KCNAB1 |
| Family | IPR005983 | Potassium channel, voltage-dependent, beta subunit, KCNAB |
| Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
| Protein | Length | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily | Potassium channel, voltage-dependent, beta subunit, KCNAB | Potassium channel, voltage-dependent, beta subunit, KCNAB1 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PRF1
|
399 | |||||
|
UniProtKB:A0A8M3AQ10
|
413 | |||||
|
UniProtKB:A0A8M9PXK3
|
348 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnab1b-201
(1)
|
Ensembl | 1,128 nt | ||
| mRNA |
kcnab1b-202
(1)
|
Ensembl | 2,034 nt |
Interactions and Pathways
No data available
Plasmids
No data available