ZFIN is now using GRCz12tu for Genomic Data
Gene
tmem70
- ID
- ZDB-GENE-070912-593
- Name
- transmembrane protein 70
- Symbol
- tmem70 Nomenclature History
- Previous Names
-
- si:dkey-82k12.6
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to act upstream of or within axis elongation and gastrulation with mouth forming second. Predicted to be active in mitochondrial membrane. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 2. Orthologous to human TMEM70 (transmembrane protein 70).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex V (ATP synthase) deficiency nuclear type 2 | Alliance | Mitochondrial complex V (ATP synthase) deficiency, nuclear type 2 | 614052 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | TMEM70 family | TMEM70/TMEM186/TMEM223 protein family |
|---|---|---|---|---|
| UniProtKB:E7FGK5 | InterPro | 248 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem70-201
(1)
|
Ensembl | 974 nt | ||
| mRNA |
tmem70-202
(1)
|
Ensembl | 806 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers