Gene

abcb6b

ID

ZDB-GENE-070912-584

Name

ATP binding cassette subfamily B member 6 (LAN blood group) b

Symbol

abcb6b Nomenclature History

Previous Names

si:dkey-7j20.1

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have ATPase-coupled heme transmembrane transporter activity and heme binding activity. Predicted to be involved in heme transport and transmembrane transport. Predicted to localize to integral component of membrane and vacuolar membrane. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcb6b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
dyschromatosis universalis hereditaria	Alliance	Dyschromatosis universalis hereditaria 3	615402
		Microphthalmia/coloboma 7	614497
		Pseudohyperkalemia, familial, 2, due to red cell leak	609153
		[Blood group, Langereis system]	111600

Associated With abcb6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR039421	Type 1 protein exporter
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC transporter-like, ATP-binding domain	ABC transporter-like, conserved site	ABC transporter type 1, transmembrane domain	ABC transporter type 1, transmembrane domain superfamily	P-loop containing nucleoside triphosphate hydrolase	Type 1 protein exporter
UniProtKB:A0A8M9Q4W6 InterPro	683
UniProtKB:A0A8M2BF06 InterPro	648
UniProtKB:A0A8M9QB69 InterPro	422

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	abcb6b-201 (1) Ensembl	Ensembl		2,052 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations