Gene
slc1a8b
- ID
- ZDB-GENE-070912-552
- Name
- solute carrier family 1 member 8b
- Symbol
- slc1a8b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in cerebellum; optic tectum; and telencephalon.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rico et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dicarboxylate/Amino Acid:Cation Symporter | Sodium:dicarboxylate symporter | Sodium:dicarboxylate symporter, conserved site | Sodium:dicarboxylate symporter superfamily |
|---|---|---|---|---|---|
|
UniProtKB:D7RVS7
|
550 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc1a8b-201
(1)
|
Ensembl | 1,695 nt | ||
| mRNA |
slc1a8b-202
(1)
|
Ensembl | 1,583 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-52K20 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001190816 (1) | 1695 nt | ||
| Genomic | GenBank:BX649372 (1) | 249584 nt | ||
| Polypeptide | UniProtKB:D7RVS7 (1) | 550 aa |
No data available
- Wang, J., Jia, B., Li, Y., Ren, B., Liang, H., Yan, D., Xie, H., Zhang, X., Liang, H. (2020) Effects of multi-walled carbon nanotubes on the enantioselective toxicity of the chiral insecticide indoxacarb toward zebrafish (Danio rerio). Journal of hazardous materials. 397:122724
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Gesemann, M., Lesslauer, A., Maurer, C.M., Schönthaler, H.B., and Neuhauss, S.C. (2010) Phylogenetic analysis of the vertebrate excitatory/neutral amino acid transporter (SLC1/EAAT) family reveals lineage specific subfamilies. BMC Evolutionary Biology. 10:117
- Gesemann, M., Maurer, C.M., and Neuhauss, S.C. (2010) Excitatory amino acid transporters in the zebrafish: Letter to "Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafish brain" from Rico et al. Brain research bulletin. 83(5):202-206
- Rico, E.P., de Oliveira, D.L., Rosemberg, D.B., Mussulini, B.H., Bonan, C.D., Dias, R.D., Wofchuk, S., Souza, D.O., and Bogo, M.R. (2010) Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafish brain. Brain research bulletin. 81(4-5):517-523
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