ZFIN ID: ZDB-GENE-070912-525 |
Gene Name: | pappalysin 2 | ||||||
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Gene Symbol: | pappa2 Nomenclature History | ||||||
Previous Name: | si:dkey-39f8.1 | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 2 Mapping Details/Browsers | ||||||
Description: | Exhibits peptidase activity. Involved in several processes, including angiogenesis; notochord development; and regulation of Notch signaling pathway. Is expressed in several structures, including axial mesoderm; bone tissue; nervous system; pleuroperitoneal region; and ventral mandibular arch. Orthologous to human PAPPA2 (pappalysin 2). | ||||||
Genome Resources: | Alliance (1), Gene:567038 (1), |
All Expression Data: | Fig. 2 from Kjaer-Sorensen et al., 2014 |
Wild-type Stages, Structures: | Blastula:1k-cell (3.0h-3.33h) to Adult (90d-730d, breeding adult) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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sa17244 | Point Mutation | Unknown | Premature Stop | ENU |
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sa25852 | Point Mutation | Unknown | Splice Site | ENU | |
sa32959 | Point Mutation | Unknown | Premature Stop | ENU |
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sa32960 | Point Mutation | Unknown | Premature Stop | ENU |
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sa32961 | Point Mutation | Unknown | Premature Stop | ENU |
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sa39870 | Point Mutation | Unknown | Premature Stop | ENU |
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sa44537 | Point Mutation | Unknown | Unknown | ENU |
Targeting Reagent | Created Alleles | Publications |
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MO1-pappa2 | N/A | 1 |
MO2-pappa2 | N/A | 1 |
MO3-pappa2 | N/A | 1 |
Data: | 4 figures from Kjaer-Sorensen et al., 2014 |
Observed in: |
Ontology | GO Term |
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Biological Process | angiogenesis (more) |
Molecular Function | peptidase activity (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
pappa2-201
(1)
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6727 |
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Browsers: NCBI |
pappa2 Contained in: | [BAC] CH211-153C18 (1) (order this), DKEY-21A8 (1) (order this), DKEY-39F8 (1) (order this) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:XM_690325 (1) | 6684 bp |
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Genomic | GenBank:CR388403 (1) | 159100 bp | |
Polypeptide | UniProtKB:E9QCK7 (1) | 1731 aa |
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