Gene
dgkh
- ID
- ZDB-GENE-070912-328
- Name
- diacylglycerol kinase, eta
- Symbol
- dgkh Nomenclature History
- Previous Names
-
- si:ch211-93a19.1
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable ATP-dependent diacylglycerol kinase activity. Predicted to be involved in diacylglycerol metabolic process; intracellular signal transduction; and phosphatidic acid biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in Purkinje cell. Orthologous to human DGKH (diacylglycerol kinase eta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Takeuchi et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000756 | Diacylglycerol kinase, accessory domain |
| Domain | IPR001206 | Diacylglycerol kinase, catalytic domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR047480 | Diacylglycerol kinase eta, second protein kinase C conserved region 1 |
| Domain | IPR054474 | Diacylglycerol kinase eta/delta/kappa, helical domain |
| Family | IPR037607 | Diacylglycerol kinase |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR016064 | NAD kinase/diacylglycerol kinase-like domain superfamily |
| Homologous_superfamily | IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C1-like domain superfamily | Diacylglycerol kinase | Diacylglycerol kinase, accessory domain | Diacylglycerol kinase, catalytic domain | Diacylglycerol kinase eta/delta/kappa, helical domain | Diacylglycerol kinase eta, second protein kinase C conserved region 1 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal | NAD kinase/diacylglycerol kinase-like domain superfamily | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PSF8 | InterPro | 197 | |||||||||||||
| UniProtKB:A0A8M2BFF5 | InterPro | 1257 | |||||||||||||
| UniProtKB:A0A8M9PSN5 | InterPro | 1107 | |||||||||||||
| UniProtKB:A0A8M3B2L0 | InterPro | 1306 | |||||||||||||
| UniProtKB:A0A8M3AVY2 | InterPro | 1251 | |||||||||||||
| UniProtKB:A0A8M9PA12 | InterPro | 246 | |||||||||||||
| UniProtKB:A0A8M9QFV5 | InterPro | 1329 | |||||||||||||
| UniProtKB:A0A8M9PLC4 | InterPro | 224 | |||||||||||||
| UniProtKB:A0AB32TYF7 | InterPro | 1284 | |||||||||||||
| UniProtKB:A0AB32U0E8 | InterPro | 1084 | |||||||||||||
| UniProtKB:A0AB32U2Y1 | InterPro | 1055 |
Interactions and Pathways
No data available
Plasmids
No data available