Gene

kcnq3

ID
ZDB-GENE-070912-301
Name
potassium voltage-gated channel, KQT-like subfamily, member 3
Symbol
kcnq3 Nomenclature History
Previous Names
  • si:ch211-66b9.3
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable voltage-gated potassium channel activity. Acts upstream of or within chemical synaptic transmission. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Is expressed in central nervous system; heart; and inner ear. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chege et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnq3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
benign neonatal seizures Alliance Seizures, benign neonatal, 2 121201
1 - 1 of 1
Associated With kcnq3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR020969 Ankyrin-G binding site
Domain IPR005821 Ion transport domain
Domain IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
Family IPR003937 Potassium channel, voltage dependent, KCNQ
Family IPR003948 Potassium channel, voltage dependent, KCNQ3
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length Ankyrin-G binding site Ion transport domain Potassium channel, voltage dependent, KCNQ Potassium channel, voltage dependent, KCNQ3 Potassium channel, voltage dependent, KCNQ, C-terminal
UniProtKB:A0A8M9PFX9 InterPro 409
UniProtKB:A0A8M3APZ9 InterPro 396
UniProtKB:A0A8M3AXH4 InterPro 795
UniProtKB:A0A8M9PAJ1 InterPro 401
UniProtKB:A0A8M9PQX0 InterPro 795
1 - 5 of 5
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kcnq3-201 (1) Ensembl 2,519 nt
mRNA kcnq3-202 (1) Ensembl 1,186 nt
mRNA kcnq3-203 (1) Ensembl 1,354 nt
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations