hbl4

ID

ZDB-GENE-070912-287

Name

hexose-binding lectin 4

Symbol

hbl4 Nomenclature History

Previous Names

si:ch211-284o19.5

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable carbohydrate binding activity. Predicted to be involved in innate immune response. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in extracellular space and multivesicular body. Human ortholog(s) of this gene implicated in several diseases, including bacterial infectious disease (multiple); fungal infectious disease (multiple); liver disease (multiple); lung disease (multiple); and vasculitis (multiple). Orthologous to human MBL2 (mannose binding lectin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hbl4 Human Ortholog

No data available

Associated With hbl4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018378	C-type lectin, conserved site
Domain	IPR001304	C-type lectin-like
Domain	IPR033990	Collectin, C-type lectin-like domain
Family	IPR051077	Calcium-dependent Lectin
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Repeat	IPR008160	Collagen triple helix repeat