Gene
myo10
- ID
- ZDB-GENE-070912-277
- Name
- myosin X
- Symbol
- myo10 Nomenclature History
- Previous Names
-
- myo10b (1)
- myo10l2
- si:ch211-283p23.2
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and plus-end directed microfilament motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport; regulation of cell shape; and regulation of filopodium assembly. Predicted to be located in cytoplasm. Predicted to be active in filopodium. Is expressed in midbrain hindbrain boundary; otic vesicle; and rhombomere. Orthologous to human MYO10 (myosin X).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Sittaramane et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000299 | FERM domain |
| Domain | IPR000857 | MyTH4 domain |
| Domain | IPR001609 | Myosin head, motor domain-like |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Domain | IPR031971 | Unconventional myosin-X, coiled coil domain |
| Domain | IPR036124 | Class X myosin, motor domain |
| Domain | IPR040640 | Myosin X, N-terminal SH3 domain |
| Domain | IPR041797 | Myosin X, FERM domain C-lobe |
| Family | IPR051724 | Actin-based Motor Myosin |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
| Homologous_superfamily | IPR038185 | MyTH4 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Actin-based Motor Myosin | Band 4.1 domain | Class X myosin, motor domain | FERM/acyl-CoA-binding protein superfamily | FERM central domain | FERM domain | FERM superfamily, second domain | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Myosin head, motor domain-like | Myosin X, FERM domain C-lobe | Myosin X, N-terminal SH3 domain | MyTH4 domain | MyTH4 domain superfamily | PH-like domain superfamily | Pleckstrin homology domain | P-loop containing nucleoside triphosphate hydrolase | Ras-associating domain | Unconventional myosin-X, coiled coil domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P844 | InterPro | 1425 | |||||||||||||||||||
| UniProtKB:A0A8M6Z236 | InterPro | 1425 | |||||||||||||||||||
| UniProtKB:A0A8M9PXE2 | InterPro | 2069 | |||||||||||||||||||
| UniProtKB:B0S541 | InterPro | 2069 | |||||||||||||||||||
| UniProtKB:A0A8M3B0G0 | InterPro | 2013 |
Interactions and Pathways
No data available
Plasmids
No data available