Gene
si:ch211-195h23.3
- ID
- ZDB-GENE-070912-174
- Name
- si:ch211-195h23.3
- Symbol
- si:ch211-195h23.3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in nucleus. Is expressed in kidney and spleen. Orthologous to several human genes including GBP1 (guanylate binding protein 1); GBP2 (guanylate binding protein 2); and GBP3 (guanylate binding protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chang et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CARD8/ASC/NALP1, CARD domain | CARD domain | Death-like domain superfamily | FIIND domain | NLRP Inflammasome |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QAJ2 | InterPro | 658 | |||||
| UniProtKB:A0A8M9QJG0 | InterPro | 469 | |||||
| UniProtKB:A0A8M9QF56 | InterPro | 917 | |||||
| UniProtKB:A0A8M9QAI5 | InterPro | 998 | |||||
| UniProtKB:A0A8M9PRT1 | InterPro | 730 | |||||
| UniProtKB:A0A8M9PRS7 | InterPro | 996 | |||||
| UniProtKB:B0V1H3 | InterPro | 478 | |||||
| UniProtKB:A0A8M9Q4E9 | InterPro | 1001 | |||||
| UniProtKB:A0A8M9QAI8 | InterPro | 970 | |||||
| UniProtKB:A0AB32TTJ9 | InterPro | 458 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-195h23.3-201
(1)
|
Ensembl | 1,830 nt |
Interactions and Pathways
No data available
Plasmids
No data available