Gene

asap1a

ID

ZDB-GENE-070912-129

Name

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a

Symbol

asap1a Nomenclature History

Previous Names

si:ch211-160i2.3

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable GTPase activator activity. Acts upstream of or within defense response to bacterium and positive regulation of macrophage migration. Predicted to be located in cytoplasm. Is expressed in head. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Cui et al., 2020

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With asap1a Human Ortholog

No data available

Associated With asap1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001164	Arf GTPase activating protein
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR004148	BAR domain
Domain	IPR037844	ASAP, PH domain
Domain	IPR037928	ASAP1, BAR domain
Domain	IPR038016	ASAP1, SH3 domain
Family	IPR043593	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Homologous_superfamily	IPR037278	ARFGAP/RecO-like zinc finger
Homologous_superfamily	IPR038508	ArfGAP domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	AH/BAR domain superfamily	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	ArfGAP domain superfamily	ARFGAP/RecO-like zinc finger	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein	Arf GTPase activating protein	ASAP1, BAR domain	ASAP1, SH3 domain	ASAP, PH domain	BAR domain	PH-like domain superfamily	Pleckstrin homology domain	SH3 domain	SH3-like domain superfamily
UniProtKB:A0A8M2BAL2 InterPro	1100
UniProtKB:A0A0R4IM47 InterPro	1097
UniProtKB:A0A8M2BAX6 InterPro	1151
UniProtKB:B3DI91 InterPro	1077
UniProtKB:A0A8M2BAL0 InterPro	1154

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	asap1a-201 (1) Ensembl	Ensembl	3,421 nt	Select Tool ZFIN BLAST
mRNA	asap1a-202 (1) Ensembl	Ensembl	3,615 nt	Select Tool ZFIN BLAST
mRNA	asap1a-203 (1) Ensembl	Ensembl	8,880 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations