Gene
ftr30
- ID
- ZDB-GENE-070912-106
- Name
- finTRIM family, member 30
- Symbol
- ftr30 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable ligase activity and zinc ion binding activity. Predicted to act upstream of or within immune system process. Predicted to be located in cytoplasm.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR003879 | Butyrophylin-like, SPRY domain |
| Domain | IPR006574 | SPRY-associated |
| Family | IPR051051 | E3 ubiquitin-protein ligase TRIM/RNF |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | B-box-type zinc finger | Butyrophylin-like, SPRY domain | Concanavalin A-like lectin/glucanase domain superfamily | E3 ubiquitin-protein ligase TRIM/RNF | SPRY-associated | SPRY domain | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1RSE3 | InterPro | 560 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-150H8 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_003197985 (1) | 2690 nt | ||
| Genomic | GenBank:BX323812 (1) | 153556 nt | ||
| Polypeptide | UniProtKB:A0A8M1RSE3 (1) | 560 aa |
No data available
- Chen, B., Huo, S., Liu, W., Wang, F., Lu, Y., Xu, Z., Liu, X. (2019) Fish-specific finTRIM FTR36 triggers IFN pathway and mediates inhibition of viral replication. Fish & shellfish immunology. 84:876-884
- Liu, W., Kuang, M., Zhang, Z., Lu, Y., Liu, X. (2019) Molecular Characterization and Expression Analysis of ftr01, ftr42, and ftr58 in Zebrafish (Danio rerio). Virologica Sinica. 34(4):434-443
- Langevin, C., Levraud, J.P., Boudinot, P. (2018) Fish antiviral tripartite motif (TRIM) proteins. Fish & shellfish immunology. 86:724-733
- Boudinot, P., van der Aa, L.M., Jouneau, L., Du Pasquier, L., Pontarotti, P., Briolat, V., Benmansour, A., and Levraud, J.P. (2011) Origin and Evolution of TRIM Proteins: New Insights from the Complete TRIM Repertoire of Zebrafish and Pufferfish. PLoS One. 6(7):e22022
- van der Aa, L.M., Levraud, J.P., Yahmi, M., Lauret, E., Briolat, V., Herbomel, P., Benmansour, A., and Boudinot, P. (2009) A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish. BMC Biology. 7:7
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