Gene

timp4.3

ID
ZDB-GENE-070824-1
Name
TIMP metallopeptidase inhibitor 4, tandem duplicate 3
Symbol
timp4.3 Nomenclature History
Previous Names
  • TIMP2d (1)
  • timp4
  • timp4a
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of proteolysis; response to cytokine; and response to hormone. Predicted to localize to extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With timp4.3 Human Ortholog
No data available
Associated With timp4.3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030490 Tissue inhibitor of metalloproteinase, conserved site
Domain IPR001134 Netrin domain
Family IPR001820 Protease inhibitor I35 (TIMP)
Homologous_superfamily IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
Homologous_superfamily IPR027465 Proteinase inhibitor I35b (TIMP), C-terminal
Domain Details Per Protein
Protein Length Netrin domain Protease inhibitor I35 (TIMP) Proteinase inhibitor I35b (TIMP), C-terminal Tissue inhibitor of metalloproteinase, conserved site Tissue inhibitor of metalloproteinases-like, OB-fold
UniProtKB:A0A0R4IT47 198
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations