Gene

adamts15b

ID

ZDB-GENE-070814-5

Name

ADAM metallopeptidase with thrombospondin type 1 motif, 15b

Symbol

adamts15b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization and proteolysis. Predicted to be active in extracellular matrix.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Brunet et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adamts15b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Arthrogryposis, distal, type 12	620545

Associated With adamts15b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001590	Peptidase M12B, ADAM/reprolysin
Domain	IPR002870	Peptidase M12B, propeptide
Domain	IPR006586	ADAM, cysteine-rich domain
Domain	IPR010294	ADAMTS/ADAMTS-like, Spacer 1
Domain	IPR041645	ADAMTS, cysteine-rich domain 2
Domain	IPR045371	ADAMTS/ADAMTS-like, cysteine-rich domain 3
Family	IPR013273	ADAMTS/ADAMTS-like
Family	IPR050439	ADAMTS and ADAMTS-like
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat

Domain Details Per Protein

Protein	Additional Resources	Length	ADAM, cysteine-rich domain	ADAMTS/ADAMTS-like	ADAMTS/ADAMTS-like, cysteine-rich domain 3	ADAMTS/ADAMTS-like, Spacer 1	ADAMTS and ADAMTS-like	ADAMTS, cysteine-rich domain 2	Metallopeptidase, catalytic domain superfamily	Peptidase M12B, ADAM/reprolysin	Peptidase M12B, propeptide	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:X1WDJ8	InterPro	935
UniProtKB:A0A8M9Q1S2	InterPro	935

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	adamts15-202 (1) Ensembl	Ensembl	2,637 nt	Select Tool ZFIN BLAST
mRNA	adamts15b-201 (1) Ensembl	Ensembl	3,327 nt	Select Tool ZFIN BLAST
mRNA	adamts15b-203 (1) Ensembl	Ensembl	4,211 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations