Gene

adam15

ID

ZDB-GENE-070809-4

Name

ADAM metallopeptidase domain 15

Symbol

adam15 Nomenclature History

Previous Names

si:dkey-24i24.1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable integrin binding activity and metallopeptidase activity. Predicted to be involved in innate immune response and integrin-mediated signaling pathway. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be active in extracellular space. Orthologous to human ADAM15 (ADAM metallopeptidase domain 15).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adam15 Human Ortholog

No data available

Associated With adam15 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001590	Peptidase M12B, ADAM/reprolysin
Domain	IPR001762	Disintegrin domain
Domain	IPR002870	Peptidase M12B, propeptide
Domain	IPR006586	ADAM, cysteine-rich domain
Domain	IPR034027	Reprolysin domain, adamalysin-type
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036436	Disintegrin domain superfamily

Domain Details Per Protein

Protein	Length	ADAM, cysteine-rich domain	Disintegrin domain	Disintegrin domain superfamily	EGF-like domain	Metallopeptidase, catalytic domain superfamily	Peptidase M12B, ADAM/reprolysin	Peptidase M12B, propeptide	Reprolysin domain, adamalysin-type
UniProtKB:A0A8M1PUF0 InterPro	992
UniProtKB:A0A8M9PDM9 InterPro	969
UniProtKB:A0A8M9PN22 InterPro	902
UniProtKB:A0A8M2B4D4 InterPro	919
UniProtKB:E7FGJ0 InterPro	975

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	adam15-201 (1) Ensembl	Ensembl		7,204 nt	Select Tool ZFIN BLAST
mRNA	adam15-202 (1) Ensembl	Ensembl		2,424 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations