Gene

adam8b

ID

ZDB-GENE-070808-1

Name

ADAM metallopeptidase domain 8b

Symbol

adam8b Nomenclature History

Previous Names

CD156b

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Is expressed in ovarian follicle stage I; ovarian follicle stage II; ovarian follicle stage III; and ovarian follicle stage IV. Orthologous to human ADAM8 (ADAM metallopeptidase domain 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adam8b Human Ortholog

No data available

Associated With adam8b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018358	Disintegrin, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001590	Peptidase M12B, ADAM/reprolysin
Domain	IPR001762	Disintegrin domain
Domain	IPR002870	Peptidase M12B, propeptide
Domain	IPR006586	ADAM, cysteine-rich domain
Domain	IPR013111	EGF-like domain, extracellular
Domain	IPR034027	Reprolysin domain, adamalysin-type
Homologous_superfamily	IPR024079	Metallopeptidase, catalytic domain superfamily
Homologous_superfamily	IPR036436	Disintegrin domain superfamily

Domain Details Per Protein

Protein	Length	ADAM, cysteine-rich domain	Disintegrin, conserved site	Disintegrin domain	Disintegrin domain superfamily	EGF-like domain	EGF-like domain, extracellular	Metallopeptidase, catalytic domain superfamily	Peptidase M12B, ADAM/reprolysin	Peptidase M12B, propeptide	Reprolysin domain, adamalysin-type
UniProtKB:A0A8M3AY73 InterPro	794
UniProtKB:E7F6J8 InterPro	819

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	adam8b-201 (1) Ensembl	Ensembl		3,402 nt	Select Tool ZFIN BLAST
mRNA	adam8b-202 (1) Ensembl	Ensembl		741 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations