Gene
col4a2
- ID
- ZDB-GENE-070725-3
- Name
- collagen, type IV, alpha 2
- Symbol
- col4a2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have extracellular matrix structural constituent. Predicted to be involved in extracellular matrix organization. Predicted to localize to basement membrane and extracellular space. Is expressed in eye; head; hypodermis; optic fissure; and optic furrow. Human ortholog(s) of this gene implicated in atherosclerosis and porencephaly. Orthologous to human COL4A2 (collagen type IV alpha 2 chain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| brain small vessel disease 2 | Alliance | Brain small vessel disease 2 | 614483 |
| {Hemorrhage, intracerebral, susceptibility to} | 614519 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Collagen IV, non-collagenous | Collagen IV, non-collagenous domain superfamily | Collagen superfamily | Collagen triple helix repeat | C-type lectin fold |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z838
|
1670 | |||||
|
UniProtKB:A0A8M9QB43
|
1636 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
col4a2-201
(1)
|
Ensembl | 5,010 nt | ||
| mRNA |
col4a2-202
(1)
|
Ensembl | 3,114 nt |
Interactions and Pathways
No data available
Plasmids
No data available