Gene

daam2

ID
ZDB-GENE-070709-1
Name
dishevelled associated activator of morphogenesis 2
Symbol
daam2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable actin binding activity. Predicted to be involved in negative regulation of oligodendrocyte differentiation; positive regulation of canonical Wnt signaling pathway; and regulation of non-canonical Wnt signaling pathway. Predicted to act upstream of or within actin cytoskeleton organization. Orthologous to human DAAM2 (dishevelled associated activator of morphogenesis 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With daam2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nephrotic syndrome, type 24 619263
Associated With daam2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR010472 Formin, FH3 domain
Domain IPR010473 Formin, GTPase-binding domain
Domain IPR014767 Diaphanous autoregulatory (DAD) domain
Domain IPR014768 Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain IPR015425 Formin, FH2 domain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR042201 Formin, FH2 domain superfamily
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold Diaphanous autoregulatory (DAD) domain Formin, FH2 domain Formin, FH2 domain superfamily Formin, FH3 domain Formin, GTPase-binding domain Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:A0A2R8Q7Y7 1028
UniProtKB:A0A286Y857 1089
UniProtKB:A0A2R8QKQ8 1018
UniProtKB:X1WFQ5 433
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations