Gene
myhz1.2
- ID
- ZDB-GENE-070705-73
- Name
- myosin, heavy polypeptide 1.2, skeletal muscle
- Symbol
- myhz1.2 Nomenclature History
- Previous Names
-
- fmyhc1.2 (1)
- ns:zf-e523
- si:ch211-158m24.8
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to localize to myosin complex. Human ortholog(s) of this gene implicated in disease of cellular proliferation; distal arthrogryposis type 2A; distal arthrogryposis type 2B1; distal arthrogryposis type 2B3; and distal arthrogryposis type 7. Is expressed in cephalic musculature and trunk. Orthologous to several human genes including MYH1 (myosin heavy chain 1) and MYH8 (myosin heavy chain 8).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR002928 | Myosin tail |
Domain | IPR004009 | Myosin, N-terminal, SH3-like |
Homologous_superfamily | IPR008989 | Myosin S1 fragment, N-terminal |
Homologous_superfamily | IPR014751 | DNA repair protein XRCC4-like, C-terminal |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
Protein | Length | DNA repair protein XRCC4-like, C-terminal | Kinesin motor domain superfamily | Myosin, N-terminal, SH3-like | Myosin S1 fragment, N-terminal | Myosin tail | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QEC8
|
1937 | ||||||
UniProtKB:A0A2R8Q2N5
|
1935 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
myhz1.2-201
(1)
|
Ensembl | 6,016 nt | ||
mRNA |
myhz1.2-202
(1)
|
Ensembl | 5,975 nt |
Interactions and Pathways
No data available
Plasmids
No data available