Gene
wasf1
- ID
- ZDB-GENE-070705-555
- Name
- WASP family member 1
- Symbol
- wasf1 Nomenclature History
- Previous Names
-
- si:dkeyp-88f5.5
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in several cellular components, including anchoring junction; cytoskeleton; and synapse. Predicted to be part of SCAR complex. Predicted to be active in lamellipodium. Orthologous to human WASF1 (WASP family member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with absent language and variable seizures | 618707 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | SCAR/WAVE family | WH2 domain |
|---|---|---|---|---|
| UniProtKB:A0A8M1Q749 | InterPro | 540 |
Interactions and Pathways
No data available
Plasmids
No data available