Gene
wasf1
- ID
- ZDB-GENE-070705-555
- Name
- WASP family member 1
- Symbol
- wasf1 Nomenclature History
- Previous Names
-
- si:dkeyp-88f5.5
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Predicted to be active in lamellipodium. Orthologous to human WASF1 (WASP family member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with absent language and variable seizures | 618707 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | SCAR/WAVE family | WH2 domain |
|---|---|---|---|---|
| UniProtKB:A0A8M1Q749 | InterPro | 540 |
Interactions and Pathways
No data available
Plasmids
No data available