Gene

rragcb

ID
ZDB-GENE-070705-380
Name
Ras-related GTP binding Cb
Symbol
rragcb Nomenclature History
Previous Names
  • si:dkey-218f9.9
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in cellular response to starvation; negative regulation of autophagy; and positive regulation of TORC1 signaling. Predicted to be located in cytoplasm; endomembrane system; and membrane. Predicted to be part of Gtr1-Gtr2 GTPase complex. Predicted to be active in lysosome and nucleus. Orthologous to human RRAGC (Ras related GTP binding C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa29138Allele with one point mutationUnknownSplice SiteENU
sa36762Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
st165Allele with one insertionExon 3UnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-rragcbBouchard et al., 2023
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Human Disease
Associated With rragcb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Long-Olsen-Distelmaier syndrome 620609
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Associated With rragcb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006762 Gtr1/RagA G protein
Family IPR039400 RagC/D
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
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Domain Details Per Protein
Protein Additional Resources Length Gtr1/RagA G protein P-loop containing nucleoside triphosphate hydrolase RagC/D
UniProtKB:A0A0R4IZL6 InterPro 392
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 19
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rragcb-201 (1)
Ensembl
Ensembl 1,574 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-218F9ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:NM_001100068 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:CR853286 (1)98234 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A0R4IZL6 (1)392 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRRAGC1
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseRragc4
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
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