Gene
znrf3
- ID
- ZDB-GENE-070705-263
- Name
- zinc and ring finger 3
- Symbol
- znrf3 Nomenclature History
- Previous Names
-
- si:ct737139.3
- si:dkeyp-7c9.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable frizzled binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of Wnt signaling pathway; stem cell proliferation; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human ZNRF3 (zinc and ring finger 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ubiquitin-protein ligase ZNRF3, zinc finger, RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | ZNRF3/Arkadia E3 ubiquitin-protein ligases | ZNRF-3, ectodomain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A5WWA0 | InterPro PDB | 868 | |||||
| UniProtKB:A0A0D3QG36 | InterPro | 866 |
Interactions and Pathways
No data available
Plasmids
No data available