Gene

znrf3

ID
ZDB-GENE-070705-263
Name
zinc and ring finger 3
Symbol
znrf3 Nomenclature History
Previous Names
  • si:ct737139.3
  • si:dkeyp-7c9.3 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have frizzled binding activity and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of Wnt signaling pathway; stem cell proliferation; and ubiquitin-dependent protein catabolic process. Predicted to localize to integral component of plasma membrane. Orthologous to human ZNRF3 (zinc and ring finger 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With znrf3 Human Ortholog
No data available
Associated With znrf3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Domain IPR040700 ZNRF-3, ectodomain
Domain IPR045903 E3 ubiquitin-protein ligase ZNRF3, Zinc finger, RING-type
Family IPR051073 ZNRF3/Arkadia E3 ubiquitin-protein ligases
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase ZNRF3, Zinc finger, RING-type Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type ZNRF3/Arkadia E3 ubiquitin-protein ligases ZNRF-3, ectodomain
UniProtKB:A5WWA0 868
UniProtKB:A0A0D3QG36 866
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA znrf3-201 (1) Ensembl 2,256 nt
mRNA znrf3-202 (1) Ensembl 3,196 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations