Gene

itpa

ID
ZDB-GENE-070705-218
Name
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Symbol
itpa Nomenclature History
Previous Names
  • si:ch73-18j6.1
  • si:dkey-19f21.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have nucleoside-triphosphate diphosphatase activity. Predicted to be involved in nucleoside triphosphate catabolic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); early infantile epileptic encephalopathy 35; hepatitis C; rheumatoid arthritis; and thrombocytopenia. Orthologous to human ITPA (inosine triphosphatase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itpa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 35 Alliance Epileptic encephalopathy, early infantile, 35 616647
[Inosine triphosphatase deficiency] 613850
Associated With itpa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:A5WVX0 203
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations