Gene
abr
- ID
- ZDB-GENE-070705-146
- Name
- ABR activator of RhoGEF and GTPase
- Symbol
- abr Nomenclature History
- Previous Names
-
- im:6904863
- si:ch211-253h3.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within positive regulation of GTPase activity and protein phosphorylation. Predicted to be located in axon and dendritic spine. Predicted to be active in membrane. Orthologous to human ABR (ABR activator of RhoGEF and GTPase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6904863 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR000198 | Rho GTPase-activating protein domain |
| Domain | IPR000219 | Dbl homology domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR015123 | Bcr-Abl oncoprotein oligomerisation |
| Domain | IPR037865 | Active breakpoint cluster region-related protein, PH domain |
| Family | IPR037769 | Abr/Bcr |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036481 | Bcr-Abl oncoprotein oligomerisation domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Abr/Bcr | Active breakpoint cluster region-related protein, PH domain | Bcr-Abl oncoprotein oligomerisation | Bcr-Abl oncoprotein oligomerisation domain superfamily | C2 domain | C2 domain superfamily | Dbl homology (DH) domain superfamily | Dbl homology domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating protein domain | Rho GTPase activation protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BFX1 | InterPro | 315 | |||||||||||||
| UniProtKB:A0A8M2BJA8 | InterPro | 814 | |||||||||||||
| UniProtKB:A0A8M6YYK4 | InterPro | 643 | |||||||||||||
| UniProtKB:A5WUN5 | InterPro | 324 | |||||||||||||
| UniProtKB:A0A8M1RSL2 | InterPro | 859 | |||||||||||||
| UniProtKB:A0A8M2BJC9 | InterPro | 1061 | |||||||||||||
| UniProtKB:A0AB13AA35 | InterPro | 1061 |
Interactions and Pathways
No data available
Plasmids
No data available