Gene

igfbp5a

ID
ZDB-GENE-070620-8
Name
insulin-like growth factor binding protein 5a
Symbol
igfbp5a Nomenclature History
Previous Names
  • igfbp5b
  • zgc:165472
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have fibronectin binding activity; insulin-like growth factor I binding activity; and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to localize to extracellular space. Is expressed in several structures, including NaK ionocyte; extension; gill filament; otic vesicle; and yolk syncytial layer. Orthologous to human IGFBP5 (insulin like growth factor binding protein 5).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Liu et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With igfbp5a Human Ortholog
No data available
Associated With igfbp5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017891 Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
Domain IPR000716 Thyroglobulin type-1
Domain IPR000867 Insulin-like growth factor-binding protein, IGFBP
Family IPR012213 Insulin-like growth factor binding protein 5
Family IPR022321 Insulin-like growth factor-binding protein family 1-6, chordata
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036857 Thyroglobulin type-1 superfamily
Domain Details Per Protein
Protein Length Growth factor receptor cysteine-rich domain superfamily Insulin-like growth factor binding protein 5 Insulin-like growth factor-binding protein family 1-6, chordata Insulin-like growth factor-binding protein, IGFBP Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site Thyroglobulin type-1 Thyroglobulin type-1 superfamily
UniProtKB:A0A2R8QF69 268
UniProtKB:A5PLA3 268
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations