ZFIN is now using GRCz12tu for Genomic Data
Gene
kcnk1a
- ID
- ZDB-GENE-070620-26
- Name
- potassium channel, subfamily K, member 1a
- Symbol
- kcnk1a Nomenclature History
- Previous Names
-
- kcnk1
- im:7150627
- zgc:165664 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables outward rectifier potassium channel activity. Acts upstream of or within heart process. Predicted to be located in several cellular components, including apical plasma membrane; perikaryon; and recycling endosome. Predicted to be active in plasma membrane. Is expressed in brain and heart. Human ortholog(s) of this gene implicated in periodontitis. Orthologous to human KCNK1 (potassium two pore domain channel subfamily K member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150627 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Christensen et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013099 | Potassium channel domain |
| Family | IPR001779 | Two pore domain potassium channel, TWIK-1 |
| Family | IPR003092 | Two pore domain potassium channel, TASK family |
| Family | IPR003280 | Two pore domain potassium channel |
| Family | IPR005408 | Two pore domain potassium channel, TWIK family |
Domain Details Per Protein
| Protein | Additional Resources | Length | Potassium channel domain | Two pore domain potassium channel | Two pore domain potassium channel, TASK family | Two pore domain potassium channel, TWIK-1 | Two pore domain potassium channel, TWIK family |
|---|---|---|---|---|---|---|---|
| UniProtKB:A5PLK0 | InterPro | 338 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnk1a-201
(1)
|
Ensembl | 1,469 nt | ||
| mRNA |
kcnk1a-202
(1)
|
Ensembl | 812 nt | ||
| mRNA |
kcnk1a-203
(1)
|
Ensembl | 1,531 nt |
Interactions and Pathways
No data available
Plasmids
- Genome Browsers