Gene

rab8b

ID
ZDB-GENE-070620-16
Name
RAB8B, member RAS oncogene family
Symbol
rab8b Nomenclature History
Previous Names
  • rab8bb (1)
  • zgc:165529
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have GTPase activity. Involved in regulation of canonical Wnt signaling pathway. Predicted to localize to cytoplasmic vesicle and plasma membrane. Is expressed in brain; central nervous system; midbrain hindbrain boundary; otic placode; and otic vesicle. Orthologous to human RAB8B (RAB8B, member RAS oncogene family).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Demir et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rab8b Human Ortholog
No data available
Associated With rab8b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding domain
Family IPR001806 Small GTPase
Family IPR050305 Small GTPase superfamily, Rab
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase superfamily, Rab Small GTP-binding domain
UniProtKB:A5PLC7 209
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rab8b-201 (1) Ensembl 3,162 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations