Gene
nadsyn1
- ID
- ZDB-GENE-070615-22
- Name
- NAD synthetase 1
- Symbol
- nadsyn1 Nomenclature History
- Previous Names
-
- zgc:165489
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to have NAD+ synthase (glutamine-hydrolyzing) activity and glutaminase activity. Predicted to be involved in NAD biosynthetic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in malignant glioma. Orthologous to human NADSYN1 (NAD synthetase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Vertebral, cardiac, renal, and limb defects syndrome 3 | 618845 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003010 | Carbon-nitrogen hydrolase |
| Domain | IPR022310 | NAD/GMP synthase |
| Family | IPR003694 | NAD(+) synthetase |
| Family | IPR014445 | Glutamine-dependent NAD(+) synthetase |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR036526 | Carbon-nitrogen hydrolase superfamily |
Domain Details Per Protein
| Protein | Length | Carbon-nitrogen hydrolase | Carbon-nitrogen hydrolase superfamily | Glutamine-dependent NAD(+) synthetase | NAD/GMP synthase | NAD(+) synthetase | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A5PLA8
|
694 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
nadsyn1-201
(1)
|
Havana | 567 nt |
Interactions and Pathways
No data available
Plasmids
No data available