Gene

nadsyn1

ID

ZDB-GENE-070615-22

Name

NAD synthetase 1

Symbol

nadsyn1 Nomenclature History

Previous Names

zgc:165489

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable NAD+ synthase (glutamine-hydrolyzing) activity and glutaminase activity. Predicted to be involved in NAD+ biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human NADSYN1 (NAD synthetase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nadsyn1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Vertebral, cardiac, renal, and limb defects syndrome 3	618845

Associated With nadsyn1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003010	Carbon-nitrogen hydrolase
Domain	IPR022310	NAD/GMP synthase
Family	IPR003694	NAD(+) synthetase
Family	IPR014445	Glutamine-dependent NAD(+) synthetase
Homologous_superfamily	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily	IPR036526	Carbon-nitrogen hydrolase superfamily