Gene

vps13c

ID

ZDB-GENE-070426-4

Name

vacuolar protein sorting 13 homolog C

Symbol

vps13c Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in Parkinson's disease 23. Orthologous to human VPS13C (vacuolar protein sorting 13 homolog C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from O'Hare et al., 2016

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vps13c Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Parkinson's disease 23	Alliance	Parkinson disease 23, autosomal recessive, early onset	616840

Associated With vps13c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR009543	Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain
Domain	IPR026854	Vacuolar protein sorting-associated protein 13-like, N-terminal domain
Domain	IPR031642	VPS13, middle RBG modules
Domain	IPR031645	Vacuolar protein sorting-associated protein 13, DH-like domain
Domain	IPR031646	Vacuolar protein sorting-associated protein 13, extended chorein
Domain	IPR049424	Intermembrane lipid transfer protein VPS13, C-terminal
Family	IPR026847	Vacuolar protein sorting-associated protein 13

Domain Details Per Protein

Protein	Length	Intermembrane lipid transfer protein VPS13, C-terminal	Vacuolar protein sorting-associated protein 13	Vacuolar protein sorting-associated protein 13, DH-like domain	Vacuolar protein sorting-associated protein 13, extended chorein	Vacuolar protein sorting-associated protein 13-like, N-terminal domain	Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain	VPS13, middle RBG modules
UniProtKB:A0A8M9Q2G3 InterPro	3695
UniProtKB:A0A8M9PZ34 InterPro	3711
UniProtKB:A0A8M9Q2F4 InterPro	3695
UniProtKB:A0A8M9QCR6 InterPro	3623
UniProtKB:A0A8M9QHS1 InterPro	3627
UniProtKB:A0A8M9PRV5 InterPro	3739
UniProtKB:A0A8M9PPS2 InterPro	3739
UniProtKB:A0A8M9QHR8 InterPro	3754
UniProtKB:A0A8M9QCR2 InterPro	3751
UniProtKB:A0A8M9Q8M3 InterPro	3711
UniProtKB:A0A8M9PPR8 InterPro	3750
UniProtKB:A0A8M9P9K9 InterPro	3755
UniProtKB:A0A8M9Q2F8 InterPro	3743
UniProtKB:A0A8M9Q8L8 InterPro	3755
UniProtKB:A0A8M9PKS2 InterPro	3751
UniProtKB:A0A8M9PRV0 InterPro	3750
UniProtKB:A0A8M9P9L4 InterPro	3627
UniProtKB:A0A8M9Q2E9 InterPro	3743
UniProtKB:A0A8M9PKS9 InterPro	3623

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	vps13c-201 (1) Ensembl	Ensembl	13,930 nt	Select Tool
ncRNA	vps13c-003 (1) Ensembl	Ensembl	641 nt	Select Tool
ncRNA	vps13c-005 (1) Ensembl	Ensembl	844 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations