Gene
rhcga
- ID
- ZDB-GENE-070424-81
- Name
- Rh family, C glycoprotein a
- Symbol
- rhcga Nomenclature History
- Previous Names
-
- rhcg
- drRhcg3 (1)
- zgc:162132
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable ammonium channel activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human RHCG (Rh family C glycoprotein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ammonium transporter AmtB-like domain | Ammonium/urea transporter | Blood group Rhesus C/E/D polypeptide |
|---|---|---|---|---|---|
| UniProtKB:A4QNU4 | InterPro | 489 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-132D3 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:162132 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001089577 (1) | 2169 nt | ||
| Genomic | GenBank:CU467822 (1) | 157975 nt | ||
| Polypeptide | UniProtKB:A4QNU4 (1) | 489 aa |
- Ng, P.C.I., Chan, J.Y.W., Leung, R.K.K., Li, J., Ren, Z., Chan, A.W.H., Xu, Y., Lee, S.S., Wang, R., Ji, X., Zheng, J., Chan, D.P.C., Yew, W.W., Lee, S.M.Y. (2020) Role of oxidative stress in clofazimine-induced cardiac dysfunction in a zebrafish model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 132:110749
- Hu, Z., Dang, Y., Liu, C., Zhou, L., Liu, H. (2019) Acute exposure to ustiloxin A affects growth and development of early life zebrafish, Danio rerio. Chemosphere. 226:851-857
- Aceto, J., Nourizadeh-Lillabadi, R., Bradamante, S., Maier, J.A., Alestrom, P., van Loon, J.J., Muller, M. (2016) Effects of microgravity simulation on zebrafish transcriptomes and bone physiology-exposure starting at 5 days post fertilization. NPJ microgravity. 2:16010
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Tessadori, F., Noël, E.S., Rens, E.G., Magliozzi, R., Evers-van Gogh, I.J., Guardavaccaro, D., Merks, R.M., Bakkers, J. (2015) Nodal Signaling Range Is Regulated by Proprotein Convertase-Mediated Maturation. Developmental Cell. 32(5):631-9
- Nakada, T., Hoshijima, K., Esaki, M., Nagayoshi, S., Kawakami, K., and Hirose, S. (2007) Localization of ammonia transporter Rhcg1 in mitochondrion-rich cells of yolk sac, gill, and kidney of zebrafish and its ionic strength-dependent expression. American journal of physiology. Regulatory, integrative and comparative physiology. 293(4):R1743-1753
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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